Effect of Increasing N,N-Dimethylformamide Concentration on the Struc- ture of Polysorbate 80 Micelles
نویسنده
چکیده
The structures of micelles of the surfactant polysorbate 80 (Tween 80) in 0-50% aqueous N,N-dimethylformamide (DMF) solutions (pH 7.2, ionic strength 2.44 mM) were investigated by means of small-angle X-ray scattering. At all the tested DMF concentrations, core-shell cylinder micelles formed; that is, increasing the concentration of DMF did not result in changes in the shape of the micelles. These results indicate that increasing the concentration of polar solvents does not always result in changes in the shapes of surfactant micelles.
منابع مشابه
Morphology of polysorbate 80 (Tween 80) micelles in aqueous dimethyl sulfoxide solutions
The structures of micelles of the surfactant polysorbate 80 (Tween 80) in 0-50% aqueous dimethyl sulfoxide (DMSO) solutions (pH 7.2, ionic strength 2.44 mM) were investigated by means of small-angle X-ray scattering. At DMSO concentrations of 0-20%, core-shell cylinder micelles formed, and at 30-50% DMSO, core-shell discus micelles formed, that is, changing the hydrophobicity of the DMSO solven...
متن کاملThe role of the DCCAs in the preparation of crack-free Xerogel
Sol–gel chemistry is an efficient tool to control the morphology and reactivity of solids. Drying is the crucial step due to the capillary forces exerted during the classic ambient drying process, which induces the collapse of the wet gel porosity. The use of N, N-dimethylformamide (DMF), a newly found DCCA were found to be effective in the sol–gel synthesis of crack-free silica gel monolith fr...
متن کاملThe role of the DCCAs in the preparation of crack-free Xerogel
Sol–gel chemistry is an efficient tool to control the morphology and reactivity of solids. Drying is the crucial step due to the capillary forces exerted during the classic ambient drying process, which induces the collapse of the wet gel porosity. The use of N, N-dimethylformamide (DMF), a newly found DCCA were found to be effective in the sol–gel synthesis of crack-free silica gel monolith fr...
متن کاملEffect of Combining Resistance Training and Curcumin Supplementation on liver Enzyme in Inactive Obese and Overweight Females
Objective: Despite the prevalence of obesity related liver disease in many countries, there is still no definitive pathway for prevention and treatment. The aim of this study was to determine the effect of combining resistance training and curcumin supplementation on liver enzyme in inactive obese and overweight Females. Materials and Methods: The study was done in a quasi-experimental trial. ...
متن کاملDevelopment of Polysorbate 80/Phospholipid mixed micellar formation for docetaxel and assessment of its in vivo distribution in animal models
Docetaxel (DTX) is a very important member of taxoid family. Despite several alternative delivery systems reported recently, DTX formulated by Polysorbate 80 and alcohol (Taxotere®) is still the most frequent administration in clinical practice. In this study, we incorporated DTX into Polysorbate 80/Phospholipid mixed micelles and compared its structural characteristics, pharmacokinetics, biodi...
متن کامل